A recent MEFISTO publication (https://doi.org/10.1002/jeo2.12090) in the Journal of Experimental Orthopaedics under the lead of University of Antwerp is providing novel insights into why patients develop Post medial meniscectomy syndrome. This study was a joint effort of the University of Antwerp, Active Implants, Humanitas University and the University of Regensburg.
This study investigates the differences in tibiofemoral joint morphology between 120 patients who responded well to arthroscopic partial medial meniscectomy (APMM) and 120 patients experiencing recurrent pain two years post-surgery (medial postmeniscectomy syndrome, MPMS). Antwerp also developed a morphology-based predictive algorithm for treatment response.
Key findings:
- Patients with recurrent pain had significantly smaller knees, a wider femoral notch, and a smaller medial femoral condyle.
- Our predictive model demonstrated impressive accuracy in identifying medial postmeniscectomy syndrome (MPMS) at two years post-surgery. With shape as the sole predictor variable, the model achieved a sensitivity of 74.9% and a specificity of 81.0% in an internal cross-validation experiment.
These insights pave the way for a future morphology-based clinical decision support tool, aiding the clinician to further optimize patient selection in a data-driven way.
Driving meniscus health forward
Driving meniscus health forward